Table 2.

GDF-15 estimated in prospectively collected blood samples from 466 endometrial carcinoma patients in relation to clinicopathologic factors

VariableNMedianP
FIGO stage (1988)<0.001
 I/II3861,034.5
 III/IV801,652.5
Histologic type<0.001
 Endometrioid3791,037.0
 Nonendometrioid871,474.0
Nonendometrioid subtypes0.803d
 Clear cell201,377.5
 Serous papillary391,336.0
 Carcinosarcoma211,617.0
 Undifferentiated71,506.0
Histologic grade<0.001
 1/23131,000.0
 31531,336.0
Age, y<0.001
 <66250893.0
 ≥662161,347.0
Parity0.467
 0a691,187.0
 ≥13951,095.0
Menopausal status<0.001
 Pre/perimenopausal58777.0
 Postmenopausal4081,152.5
BMIb0.578
 <251301,131.0
 ≥252471,048.0
Lymph node metastasesc0.001
 Neg3281,006.0
 Pos461,520.0

Abbreviation: BMI, body mass index.

  • aParity information missing for 2 patients.

  • bBMI missing in 89 cases.

  • cLymph node sampling not carried out in 92 cases.

  • dKruskal–Wallis test.