Table 4.

Prediction of lymph node metastases in 370 patients with endometrial carcinoma, univariate and multivariate logistic regression

VariableNUnivariate OR95% CIPMultivariate OR95% CIP
Curettage histology0.0020.010
 Low riska27911
 High riskb912.741.45–5.202.431.24–4.75
GDF-15< 0.0010.003
 High tertile1103.071.64–5.762.781.41–5.47

NOTE: When carrying out same multivariate logistic regression, but by using LnGDF-15 as a continuous variable instead of categorized GDF-15 into high (upper tertile) and low (lower 2 tertiles) GDF-15, GDF-15 remained predictive for lymph node metastasis (adjusted OR of 2.3; 95% CI, 1.4–3.9; P = 0.001).

  • aHyperplasia and endometrioid grades 1–2.

  • bNonendometrioid and endometrioid grade 3.