Table 2

Summary of telomere length abnormalities found to date in intraepithelial neoplasia lesions by in situ telomere length assessment

Site/intraepithelial neoplasia lesionnAny abnormalities (%)Short (%)Long (%)Mixed (long & short) (%)Reference
Bladder/carcinoma in situ11100739164Current study
Large intestine/adenoma51001002020Current study
Large intestine/high-grade dysplasia21001005050Current study
Esophageal/dysplasia610010000Current study
Oral cavity/dysplasia8888800Current study
Uterine cervix/squamous intraepithelial neoplasia310010000Current study
Prostate/prostatic intraepithelial neoplasia45969600 34 , 35
Pancreas/pancreatic intraepithelial neoplasia82969600 36
Breast/ductal carcinoma in situ23837844 59
Bile duct/dysplasia111009190 Footnote 4
 Averages95%92%7%5%
 Total number of lesions = 196