Table 1

Expression of matrix metalloproteinase (MMP)-2 and -9, membrane-type 1 (MT1)- and type 2 (MT2)-MMP, and their tissue inhibitors (TIMP-1, -2, and -3) in 83 patients with classical medullablastoma and 18 with desmoplastic medulloblastoma

Total (n)MMP-2, n (%)MMP-9, n (%)MT1-MMP, n (%)MT2-MMP, n (%)TIMP-1, n (%)TIMP-2, n (%)TIMP-3, n (%)
All10134 (34)87 (87)77 (77)81 (81)23 (23)49 (49)62 (62)
Histology
 Classical8331 (37)62 (75)62 (75)63 (76)23 (28)34 (41)56 (67)
 Desmoplastic183 (17)15 (83)15 (83)18 (100)015 (83)6 (33)
P a 0.09NSbNS0.020.0080.0010.007
  • a Pearson’s χ2 test was used to assess the significance.

  • b NS, not significant.