Table 1

Cytolytic activity of splenocytes from IL-2-treated mice against NXS2 and YAC-1 targetsa

Mice treated withYAC-1NXS2NXS2 + hu14.18-IL2b
c.i. PBS8 ± 18 ± 1113 + 4
c.i. IL-296 ± 2311 + 159 ± 2
  • a Splenocytes were harvested from four A/J mice after 6 days of continuous s.c. infusion of PBS or 50,000 IU/day recombinant human IL-2 and used as effector cells. The 4 h 51Cr release assay was performed in medium alone or medium supplemented with hu14.18-IL2 (5 μg/ml). Results are expressed as the mean lytic unit values ± SE for three experiments.

  • b IL-2, interleukin 2.