Table 3

Cycle 1 toxicities with docetaxel and flavopiridol

Docetaxel, mg/m26060505050
Flavopiridol, m/m2/d5028263420
Duration of infusion, h7272111
No. of patients23312
EventG1G2G3G4G1G2G3G4G1G2G3G4G1G2G3G1G2G3G4
Neutropenia2221111
Thrombocytopenia111
Diarrhea22111
Nausea1111
Vomiting11
Anorexia21
Fatigue1112211
Myalgia12
Hypotension1111
Tumor pain1
Hypoalbuminemia11121
Hypophosphatemia12
  • Abbreviation: G, grade.