Correlation between B7-DC expression on tumor cells and the clinicopathological characteristics of the 52 non-small cell lung cancers
| B7-DC+ expression on tumor cells | P | |||
|---|---|---|---|---|
| Low (<8%) | High (≥8%) | |||
| Patients | 26 | 26 | ||
| Age (mean ± SD) (yrs) | 66.0 ± 1.6 | 66.9 ± 2.3 | 0.73* | |
| Sex | ||||
| Male | 18 | 17 | 0.77† | |
| Female | 8 | 9 | ||
| Smoking habits | ||||
| Smoker | 16 | 22 | 0.06† | |
| Nonsmoker | 10 | 4 | ||
| Histology | ||||
| SCC | 9 | 12 | 0.06† | |
| Adenocarcinoma | 17 | 14 | ||
| Differentiation | ||||
| Well | 9 | 6 | 0.36† | |
| Moderate/poor | 17 | 20 | ||
| pT classifications | ||||
| T1 | 7 | 7 | NS† | |
| T2–4 | 19 | 19 | ||
| pN classifications | ||||
| N0 | 17 | 14 | 0.4† | |
| N1–3 | 9 | 12 | ||
| pStage classifications | ||||
| I | 14 | 11 | 0.4† | |
| II–IV | 12 | 15 | ||
| CD45+ cells‡ | 41.8 ± 3.2 | 48.8 ± 3.0 | 0.11* | |
Abbreviations: SCC, squamous cell carcinoma; NS, nonsignificant.
* Student’s paired t test.
† χ2 test.
‡ Percentage of CD45-positive cells per 1000 total nuclei.