Table 3

VDR polymorphism frequencies

Controls n (%)Allele frequencyCases n (%)Allele frequencyOdds ratio (95% CI)Odds ratio* (95% CI)Odds ratio (95% CI)
BsmI
bb139 (32.8)b 0.58173 (42.7)b 0.651.75 (1.15–2.66)1.88 (1.19–2.95)1.92 (1.20–3.10)
Bb215 (50.1)B 0.42173 (44.5)B 0.351.13 (0.75–1.70)1.07 (0.69–1.65)1.00 (0.63–1.59)
BB73 (17.1)52 (12.8)1.001.001.00
Poly(A)
 LL141 (33.0)L 0.58169 (42.4)L 0.651.70 (1.11–2.60)§1.90 (1.20–3.01)1.94 (1.20–3.14)
 LS215 (50.4)S 0.42179 (45.0)S 0.351.18 (0.78–1.79)1.17 (0.75–1.82)1.10 (0.70–1.77)
 SS71 (16.6)50 (12.6)1.001.001.00
FokI
FF159 (37.2)F 0.60163 (40.7)F 0.641.42 (0.93–2.16)1.31 (0.84–2.06)1.33 (0.83–2.14)
Ff196 (45.9)f 0.40183 (46.0)f 0.361.29 (0.86–1.95)1.26 (0.81–1.95)1.28 (0.81–2.04)
ff72 (16.9)52 (13.3)1.001.001.00
  • * Adjusted odds ratio for age (of controls at sampling and cases at diagnosis), HRT usage, and menopausal status.

  • Adjusted odds ratio for age (of controls at sampling and cases at sampling), HRT usage, and menopausal status.

  • P < 0.01, statistically significant.

  • § P < 0.05, statistically significant.