Table 6

Association of patient and disease characteristics with survival

ParameterCategoryNo.% 2-yr survival% 4-yr survivalP (log rank)
Age (years)<6017686650.44
≥60668747
SplenomegalyNo19591680.06
Yes436751
Hemoglobin (g/dl)<129890700.01
≥121438158
WBC (×109/l)≤5019187670.03
>50508459
Platelets (×109/l)≤45016488730.01
>450778350
% peripheral basophils<720388690.03
≥7387546
Peripheral blastsNo1629270<0.01
Yes757553
% marrow basophils<41898769<0.01
≥4508147
% marrow blasts<52119068<0.01
≥5285947
Cytogenetic clonal evolutionNo20787650.70
Yes358262
Sokal risk (20)Low4789740.76
Intermediate439388
High76934
Study groupStudy group14791<0.01
IFN (historical)957855.3