Table 1

Differences in CGH alterations between CK14-positive and CR14-negative tumors

Chromosome gainOverall (%)CK14 positive (%)CK14 negative (%)P*Chromosome lossOverall (%)CK14 positive (%)CK14 negative (%)P*
1p5 (6)4 (9)1 (2)0.20771p18 (21)9 (21)9 (21)>0.9999
1q18 (21)7 (16)11 (26)0.42711q1 (1)0 (0)1 (2)>0.9999
2p7 (8)2 (5)5 (12)0.43312p11 (13)3 (7)8 (19)0.1951
2q10 (12)3 (7)7 (16)0.31342q12 (14)3 (7)9 (21)0.1171
3p8 (9)3 (7)5 (12)0.71303p10 (12)3 (7)7 (16)0.3134
3q7 (8)2 (5)5 (12)0.43313q7 (8)2 (5)5 (12)0.4331
4p4 (5)1 (2)3 (7)0.61604p7 (8)1 (2)6 (14)0.1096
4q11 (13)6 (14)5 (12)>0.9999 4q 12 (14) 2 (5) 10 (23) 0.0261
5p3 (3)0 (0)3 (7)0.24125p6 (7)1 (2)5 (12)0.2020
5q9 (10)2 (5)7 (16)0.15615q12 (14)3 (7)9 (21)0.1171
6p7 (8)1 (2)6 (14)0.10966p5 (6)2 (5)3 (7)>0.9999
6q8 (9)5 (12)3 (7)0.71306q10 (12)3 (7)7 (16)0.3134
7p6 (7)4 (9)2 (5)0.73837p6 (7)1 (2)5 (12)0.2020
7q10 (12)6 (14)4 (9)0.7383 7q 6 (7) 0 (0) 6 (14) 0.0259
8p7 (8)3 (7)4 (9)>0.99998p7 (8)2 (5)5 (12)0.4331
8q11 (13)5 (12)6 (14)>0.9999 8q 12 (14) 2 (5) 10 (23) 0.0261
9p4 (5)2 (5)2 (5)>0.9999 9p 6 (7) 0 (0) 6 (14) 0.0259
9q8 (9)5 (12)3 (7)0.71309q14 (16)5 (12)9 (21)0.3816
10p2 (2)1 (2)1 (2)>0.999910p2 (2)1 (2)1 (2)>0.9999
10q3 (3)1 (2)2 (5)>0.999910q3 (3)1 (2)2 (5)>0.9999
11p2 (2)0 (0)2 (5)0.494111p7 (8)3 (7)4 (9)>0.9999
11q6 (7)3 (7)3 (7)>0.999911q7 (8)3 (7)4 (9)>0.9999
12p6 (7)2 (5)4 (9)0.738312p6 (7)1 (2)5 (12)0.2020
12q2 (2)1 (2)1 (2)>0.999912q10 (12)2 (5)8 (19)0.0887
13q5 (6)2 (5)3 (7)>0.9999 13q 9 (10) 0 (0) 9 (21) 0.0025
14q6 (7)2 (5)4 (9)0.7383 14q 6 (7) 0 (0) 6 (14) 0.0259
15q4 (5)1 (2)3 (7)0.616015q9 (10)2 (5)7 (16)0.1561
16p2 (2)1 (2)1 (2)>0.9999 16p 16 (19) 14 (33) 2 (5) 0.0016
16q1 (1)0 (0)1 (2)>0.999916q17 (20)11 (26)6 (14)0.2787
17p 11 (13) 2 (5) 9 (21) 0.0488 17p17 (20)12 (28)5 (12)0.1025
17q 22 (26) 4 (9) 18 (42) 0.0010 17q 21 (24) 16 (37) 5 (12) 0.0110
18p6 (7)2 (5)4 (9)0.738318p3 (3)2 (5)1 (2)>0.9999
18q2 (2)1 (2)1 (2)>0.999918q14 (16)4 (9)10 (23)0.1424
19p5 (6)1 (2)4 (9)0.360019p18 (21)11 (26)7 (16)0.4271
19q5 (6)0 (0)5 (12)0.0553 19q 18 (21) 14 (33) 4 (9) 0.0155
20p 9 (10) 0 (0) 9 (21) 0.0025 20p9 (10)6 (14)3 (7)0.4833
20q 35 (41) 9 (21) 26 (60) 0.0004 20q4 (5)0 (0)4 (9)0.1162
21q6 (7)3 (7)3 (7)>0.999921q6 (7)5 (12)1 (9)0.2020
22q4 (5)0 (0)4 (9)0.116222q14 (16)8 (19)6 (14)0.7712
Xp1 (1)0 (0)1 (2)>0.9999 Xp 14 (16) 11 (26) 3 (7) 0.0381
Xq3 (3)0 (0)3 (7)0.2412Xq13 (15)7 (16)6 (14)>0.9999
  • NOTE: Numbers of tumors (and percentages) exhibiting a change in DNA copy number in all cases, as well as stratified by CK14 status are given along with the P value as determined by Fisher’s exact test to probe differences between the two groups. Significant (P < 0.05) differences in gains are in italics.

  • * Determined by Fisher’s exact test.