Table 4

Association of specific immunohistochemical and CGH data with cluster 1 tumors

FactorCluster 1 tumors (%)All other tumors (%)P (Fisher’s exact)
CK14 positive18 (78.3)25 (39.7) 0.003
ERa negative19 (82.6)34 (54.0) 0.0231
PR negative15 (65.2)32 (50.8) 0.039
1q gain10 (43.5)8 (12.7) 0.004
8p loss5 (21.7)2 (3.2) 0.0199
16p loss13 (56.5)3 (4.8)<0.0001
16q loss9 (39.1)8 (12.7) 0.0116
17p loss8 (34.8)9 (14.3) 0.0488
17q loss13 (56.5)8 (12.7) 0.0001
19p loss12 (52.2)6 (9.5) 0.0001
19q loss12 (52.2)6 (9.5) 0.0001
  • NOTE. Numbers of tumors (and percentage) exhibiting a change in DNA copy number in cluster 1 and other tumors are given along with the P value as determined by Fisher’s exact test to probe differences between the two groups. Significant (P < 0.05) differences in gains are highlighted in italics.

  • a ER, estrogen receptor; PR, progesterone receptor.

  • * Determined by Fisher’s exact test.