Table 4

Multivariate analysis of cluster group designation, tumor size, and lymph node status

Model and variablesDisease-specific survivalOverall survival
PRelative risk (99% CI)PRelative risk (99% CI)
Cluster groups (19 markers) and clinical parameters
 Cluster groups*0.0012.5 (1.2–5)0.0021.9 (1.1–3.4)
 Lymph node status0.0052.2 (1.1–4.5)0.0071.8 (1–3.1)
 Tumor size0.41.3 (0.6–2.6)0.0521.5 (0.9–2.6)
Cluster groups (11 markers) and clinical parameters
 Cluster groups*<0.0012.9 (1.5–5.7)<0.0012.2 (1.3–3.8)
 Lymph node status0.0012.4 (1.2–4.6)0.0051.8 (1–3)
 Tumor size0.111.5 (0.8–3)0.0211.6 (0.9–2.8)
  • Abbreviations: CI, confidence interval.

  • * Group 1 versus 2 and 3 (as shown on Fig. 2C and D<$REFLINK> ).