Table 3

Reported serious adverse events that were not thought to be related to Tempol

ToxicityGrade 1Grade 2Grade 3Grade 4–5
Periorbital swelling1
Right scalp swelling at incision1
Humerus fracture1
Hyperglycemia42
Hypoglycemia11
Hypokalemia3
Anemia44
↓ WBC11
Thrombocytopenia1
Hypocalcemia32
Hyponatremia1
Transaminases increased3
Alkaline phosphatase increased3
Hypoalbuminemia31
Acidosis1
Hematuria1
Fatigue32
Weakness1
Anorexia1
Nausea32
Vomiting2
Blurry vision11
Seizures1
Flashing lights (vision)1
Temporary paralysis (<10 s)1
Partial thromboplastin time increased1
Dyspnea1
Dry mouth1
Oral thrush3
Scalp hyperpigmentation1
Rash 2° dilantin1
Headache3
Memory loss1
Taste disturbance1
Scalp tingling
Occasional cough1
Death, cardiovascular1