Table 4

Immunohistochemical analysis of A431 xenografts

GroupsControl*Gefitinib (25 mg/kg)*Gefitinib (50 mg/kg)*Cetuximab (1 mg/mouse)*Gefitinib (25 mg/kg) + cetuximab (1 mg/mouse)*Gefitinib (50 mg/kg) + cetuximab (1 mg/mouse)*
pEGFR52352532132
pMAPK37251024135
pAkt3424474860
  • * Mean of percentage of tumor cell staining for each antibody.

  • P < 0.01 (Mann–Whitney U test).