Table 1

Characteristics of study participants

CharacteristicPlacebo (N = 53)Pulmicort (N = 53)
Age, y
 Median5855
 Range42–7444–74
Sex, no. (%)
 Male39 (74)38 (72)
 Female14 (26)15 (28)
Smoking history, pack-years
 Median5244
 Range30–9327–115
Smoking status, no. (%)
 Current smoker44 (83)39 (74)
 Former smoker9 (17)14 (26)*
Highest grade of dysplasia in baseline biopsy samples, no. (%)41 (77)46 (87)
 Mild12 (23)7 (13)
 Moderate/Severe41 (77)39 (74)
≥2 sites of dysplasia, no. (%)5
10-year lung cancer risk (%)(1–11)(1–11)
  • * The number of former smokers in the placebo group was not statistically significantly different from the number of former smokers in the Pulmicort group (P = 0.25; χ2 test).

  • Risk assessment using algorithm reported by Bach et al. (27) assuming the current smokers stopped smoking at enrollment.