Table 5

Toxicity effects of treatment

Placebo (N = 53)Pulmicort (N = 53)
SymptomGrade 1Grade 2Grade 3TotalGrade 1Grade 2Grade 3TotalP*
Dry throat1201131110120.82
Thirst sensation41051010110.17
Sore mouth120320021.0
Bad taste1010111520170.27
Voice change5005751130.07
Throat irritation1540191960250.32
Hoarse voice640101892290.001
Loss of voice010102020.56
Thrush010112250.21
Cough52071730200.008
Headache1140151230151.0
Fatigue1031141440180.53
Nausea11201332050.07
Blurry/itch/dry eyes10101130030.045
Skin bruising700780080.78
Cortisol suppression000050050.07
Elevated fasting blood sugar300310010.61
  • * Comparison using χ2 test for equality of proportions. Yates corrected P values.

  • Number of subjects experiencing each grade of toxicity.