Table 3

Related adverse events ≥grade 2

LErafAON dose1 mg/kg/wk2 mg/kg/wk4 mg/kg/wk6 mg/kg/wk
Grade234234234234
Allergic reaction11111
Back pain1
Chills1
Fatigue1
Fever1
Headache1
Rigors2112
Hypotension1
Anorexia1
Constipation1
Emesis1
Anemia1
Thrombocytopenia1113
Hyperbilirubinemia1
Dehydration1
Hyperglycemia1
Aspartate aminotransferase elevation11
Alanine aminotransferase elevation11
Myalgia1
Dyspnea112
Hypoxia113
Hypoalbuminemia1