Table 3

Cox proportional hazard model analysis of independent prognostic variables.

VariableParameterEstimated hazard ratio with 95% hazard ratio confidence intervalP
Overall survival
 Male0.549351.732 (0.536–5.597)0.3586
 Age ≥50 years0.854242.35 (0.765–7.218)0.1357
 G/GG0.520311.683 (0.496–5.705)0.4036
 GG/GG−0.402570.669 (0.115–3.898)0.6545
 Grade 21.726755.622 (1.106–28.571)0.0374
 Grade 33.0647121.428 (3.881–118.325)0.0004
Disease-free survival
 Male−0.034750.966 (0.407–2.294)0.9373
 Age ≥50 years0.016541.017 (0.453–2.282)0.9680
 G/GG−0.134420.874 (0.357–2.138)0.7683
 GG/GG−0.803520.448 (0.133–1.505)0.1939
 Grade 21.641655.164 (1.786–14.931)0.0024
 Grade 32.248189.470 (2.786–32.197)0.0003