Table 1

Course information by dose level

LevelLoad (mg)Maintenance (mg/day)No. of patient1 course2 courses>2 courses *
1100 × 4503120
2150 × 4507 (1 unevaluable)051 (18)
3150 × 410012 (1 unevaluable)901 (5), 1 (6)
4150 × 610014 (3 unevaluable)441 (3), 1 (4), 1 (14)
5150 × 61506 (1 unevaluable)311 (3)
Total42 (6 unevaluable)17127
  • * Numbers in parentheses indicate the number of courses received for those patients receiving more than two courses.