Table 2

Correlation between clinicopathological factors and VEGF-C expression in invasive ductal adenocarcinoma of pancreatic head

Clinicopathological factorsVEGF-C expression (%) marginal portionPVEGF-C expression (%) central portionP
Negative/lowHighNegative/lowHigh
Histology
 Well9 (15.5)15 (25.9)0.22414 (24.1)10 (17.2)0.505
 Moderately13 (22.4)19 (32.8)19 (32.8)13 (22.4)
 Poorly2 (3.4)0 (0)2 (3.4)0 (0)
Tumor size
 T12 (3.4)00.0522 (3.4)0 (0)0.561
 T23 (5.2)1 (1.7)3 (5.2)1 (1.7)
 T315 (25.9)31 (53.4)26 (44.8)20 (34.5)
 T44 (6.9)2 (3.4)4 (6.9)2 (3.4)
Lymphatic invasion
 Negative5 (8.6)1 (1.7)0.0285 (8.6)1 (1.7)0.224
 Positive19 (32.8)33 (56.9)30 (51.7)22 (37.9)
Venous invasion
 Negative8 (13.8)9 (15.5)0.5729 (15.5)8 (13.8)0.458
 Positive16 (27.6)25 (43.1)26 (44.8)15 (25.9)
Lymph node metastasis
 Negative14 (24.1)9 (15.5)0.01517 (29.3)6 (10.3)0.087
 Positive10 (17.2)25 (43.1)18 (31.0)17 (29.3)
Liver metastasis
 Negative19 (32.8)21 (36.2)0.15827 (46.6)13 (22.4)0.097
 Positive5 (8.6)13 (22.4)8 (13.8)10 (17.2)
  • NOTE. Statistical significances of association between expression level of VEGF-C in each portion and clinicopathological factors were both calculated with the χ2 test.