Table 3

Influences of several cofactors on H-RFS: multivariate analysis

VariableCases (N = 134)HR (95% CI)P value
IGF-1R expression
 Diffuse positive40Referent
 Focal positive943.70 (1.29–10.63)0.015
Depth
 Serosa negative60Referent
 Serosa positive743.32 (1.42–7.75)0.006
Lymph vessel invasion
 Absent63Referent
 Present712.48 (1.14–5.41)0.022
Venous invasion
 Absent29Referent
 Present1053.54 (0.84–14.98)NS
  • Abbreviations: W/D, well differentiated; M/D, moderately differentiated; HR, hazard ratio; CI, confidence interval; NS, not significant.