Table 4

Salivary mRNA biomarkers for OSCC selected by logistic regression model

BiomarkerCoefficient valueSEP value
Intercept−4.791.510.001
IL1B 5.10E +192.68E +190.062
OAZ1 2.18E +201.08E +200.048
SAT 2.63E +191.10E +190.020
IL8 1.36E +174.75E +160.006
  • NOTE. The logistic regression model was built based on the four of seven validated biomarkers (IL1B, OAZ1, SAT, and IL-8) that, in combination, provided the best prediction. The coefficient values are positive for these four markers, indicating that the synchronized increase in their concentrations in saliva increased the probability that the sample was obtained from an OSCC subject.