Table 2

Univariate and multivariate Cox survival analyses addressing the association between NF-κB and biochemical prostate cancer recurrence (PSA > 0.3 ng/mL and rising) after RP

Predictors variableBiochemical recurrence after RP
Univariate (rate ratio and 95% CI)Multivariate (rate ratio and 95% CI)
NF- κB4.9 (1.47–16.70); P = 0.016.2 (1.64–23.53); P = 0.007
Age (y)0.97 (0.90–1.05); P = 0.40.95 (0.88–1.03); P = 0.2
pPSA (ng/mL)0.96 (0.91–1.02); P = 0.20.91 (0.85–0.98); P = 0.01
Gleason sumP = 0.009P = 0.03
Seminal vesicle invasion2.5 (0.83–7.46); P = 0.12.2 (0.65–7.40); P = 0.2
Lymph node metastases2.2 (0.64–7.68); P = 0.24.8 (0.99–23.62); P = 0.052
  • NOTE. Covariates include age, pPSA, Gleason sum, seminal vesicle invasion, and lymph node metastases. Primary and secondary Gleason patterns were used to define the Gleason sum.