Table 3

Cytotoxicity of CTL lines (HLA-A*0201)

Start positionAA sequencesCytotoxicity (%)Start positionAA sequencesCytotoxicity (%)
Pep(+)Pep(−)Pep(+)Pep(−)
60KLNLTLEGV−2.10.281KLMQSHPLYL18.027.6
8QLAALWPWL3.50.0357YLLGPSRSAV18.215.4
82LMQSHPLYL1.71.2202LMTVVGTIFV *
358LLGPSRSAV−0.4−0.7290CLHEFHRNCV9.69.7
11ALWPWLLMA90.21.5500SLSSDFDPLV
15WLLMATLQA−0.20.08QLAALWPWLL6.79.0
200WILMTVVGT *11ALWPWLLMAT91.527.1
171KLMEFVYKN2.60.07LQLAALWPWL
62NLTLEGVFA *726WLCLTPRQPL
156GLTWPVVLI−0.40.7302WLHQHRTCPL7.46.1
  • Note. Table 3<$REFLINK> shows cytotoxicities of CTL lines with HLA-A*0201 binding peptides derived from RNF43. Pep(+) shows cytotoxicity against the targets pulsed with corresponding peptides, and Pep(−) shows cytotoxicity against targets without peptide pulse at 20 as Effector-to-Targets ratio.

  • Abbreviations: AA, amino acid(s); Pep, peptides.

  • * Peptide was not synthesized because of the technical difficulties caused by highly hydrophobic nature of the peptides.

  • CTL line was not established.