Table 4

Cytotoxicity of CTL lines (HLA-A*2402)

Start positionAA sequencesCytotoxicity (%)Start positionAA sequencesCytotoxicity (%)
Pep(+)Pep(−)Pep(+)Pep(−)
331SYQEPGRRL21449SYCTERSGYL11
350HYHLPAAYL2617350HYHLPAAYLL
639LFNLQKSSL4233718CYSNSQPVWL
24GFGRTGLVL89209IFVIILASVL *
247RYQASCRQA7182313VFNITEGDSF *
397RAPGEQQRL4132496TFCSSLSSDF89
114RAPRPCLSL232681KLMQSHPLYL105
368RPPRPGPFL1054KMDPTGKLNL52
45KAVIRVIPL 683HYTPSVAYPW00
721NSQPVWLCL680282GQELRVISCL
  • Note. Table 4<$REFLINK> shows cytotoxicities of CTL lines with HLA-A*2402 binding peptides derived from RNF43. Pep(+) shows cytotoxicity against the targets pulsed with corresponding peptides, and Pep(−) does cytotoxicity against targets without peptide pulse at 20 as Effectors to Targets ratio.

  • Abbreviations: AA, amino acid(s); Pep, peptides.

  • * Peptide was not synthesized because of the technical difficulties caused by highly hydrophobic nature of the peptides.

  • CTL line was not established.