Table 4

Correlation of clinicopathologic parameters with Cox-2 and Cox-1 expressions

Clinicopathologic parametersNumber of casesCox-2 expressionPCox-1 expressionP
NegativePositiveNegativePositive
All cases28884204165123
Age (y)288Rho = 0.0660.2605*Rho = 0.0060.9198*
Gender
 Male1835113211073
 Female10533720.522455500.2019
Tumor site
 Colon174491259381
 Rectum11435790.642772420.1033
Tumor size288Rho = 0.411<0.0001*Rho = 0.2080.0004*
Histology
 Well163451188677
 Moderate11235777042
 Poor13490.8012940.1858
Depth of invasion
 pT13917222316
 pT24821272820
 pT3174451299876
 pT4271260.000416110.9814
Lymph node metastasis
 Yes10322816043
 No185621230.0296105800.8057
Lymphatic invasion
 Yes1974914811483
 No9135560.018351400.7711
Venous invasion
 Yes2115315811794
 No7731460.012348290.2957
TNM stage
 I7835434632
 II9720775443
 III9622745244
 IV177100.00131340.3715
Recurrence
 Yes599503920
 No229751540.00841261030.1250
  • * Spearman rank test P value.