Table 5

Multivariate survival analysis: Cox proportional hazards model

ParametersβSEPRelative risk ratio95% Confidence interval
Age (<61 versus ≥61 y)0.3040.2850.28701.3550.775–2.370
Gender (female versus male)0.0800.3080.79631.0830.592–1.982
Tumor site (colon versus rectum)0.2490.2770.36831.2830.745–2.210
Tumor size (<4.0 versus ≥4.0 cm)0.6650.4460.13581.9450.811–4.662
Histology (well versus moderate, poor)−0.0930.2740.73460.9110.532–1.560
Depth of invasion (pT1,2 versus pT3,4)0.8690.6340.17062.3850.688–8.268
Venous invasion (no versus yes)0.6940.5610.21602.0020.666–6.016
Lymphatic invasion (no versus yes)0.6890.5660.22401.9910.656–6.045
Lymph node metastasis (no versus yes)0.7880.3360.01892.1991.139–4.247
TNM stage (I, II versus III, IV)1.1800.3720.00153.2551.570–6.750
Cox-1 status (negative versus positive)0.4580.2970.12341.5810.883–2.830
Cox-2 status (negative versus positive)1.4140.5510.01034.1141.397–12.120