Table 1

Genetic and biological characteristics of NB cell lines

Cell linesSubcloneSubclone typeMYCN amplificationMYCN proteinTumorigenic1p deletion11q loss17q gain
SK-N-SHNoNoNDYesNoNoYes
SK-N-BE (2)NoYesHighYesYesYesYes
NMBNoYesHighYesYesYesYes
IMR-5NoYesHighYesYesYesYes
SMS-KCNRNoYesHighYesYesNoYes
NGPNoYesHighYesNoYesYes
NBL-SNoNoModerateYesNoYesNo
NBL-W-NYesNYesHighYesYesNoNo
NBL-W-SYesSYesLowYesYesNoNo
LA1–55nYesNYesHighYesYesNoNo
LA1–5sYesSYesLowNoYesNoNo
SH-SY5YYesNNoNDYesNoNoYes
SH-EPYesSNoNDNoNoNoYes
  • Abbreviations: ND, not detected.

  • The data were summarized according to previous publications (22 23 24 25 26) .