Table 2

Statistical analyses of patient- and tumor-related variables in relation to MVD

VariablesnMedian MVD (range)P*
Age (y)
 >40331 (5–50)0.163
 ≤405758 (2–157)
Gender
 Male3458 (2–157)0.551
 Female2647 (4–135)
Tumor site
 Trunk445 (5–50)0.185
 Extremity5658 (2–157)
Primary metastases
 Absent5058 (2–157)0.215
 Detectable1048 (3–142)
Osteosarcoma
 Primary5750 (2–157)0.221
 Secondary377 (50–117)
Histological subtype
 Osteoblastic2961 (3–157)
 Fibroblastic1750 (10–105)
 Chondroblastic648 (2–60)0.661
 Teleangiectatic447 (23–114)
 Slerotic347 (31–71)
 Small cell158
Tumor response to chemotherapy (refs. 14 and 15 )
 Good (response grades 1–3)3464 (5–157)0.005
 Bad (response grades 4–6)2245 (2–114)
Surgical remission (surgical margins; ref. 16 )
 Good (radical/wide)5058 (2–157)0.639
 Bad (marginal/intralesional)649 (31–71)
  • NOTE. MVD is measured in microvessels per 0.26-mm2 field area.

  • * Mann-Whitney-test, unless otherwise indicated.

  • Kruskal-Wallis test.