Table 3

Drug sensitivity of paclitaxel-resistant Calu3 variants derived from single step paclitaxel selection

PaclitaxelVincristineDoxorubicinCisplatin
Clone from paclitaxel- treated cells
 P-21.31.10.80.9
 P-42.61.71.60.9
 P-57.53.43.30.9
 P-611.56.64.01.0
 P-78.25.43.00.9
 P-832.231.78.51.0
 P-929.116.35.90.8
 P-1012.26.53.00.9
 P-1113.97.63.50.9
 P-1213.45.54.10.9
 P-131.31.00.81.0
 P-1514.17.82.10.8
Clone from bexarotene/ paclitaxel-treated cells
 PL-20.90.81.01.0
 PL-47.74.91.90.9
 PL-81.31.00.90.8
 PL-911.95.34.00.7
 PL-101.11.10.90.7
 PL-115.66.22.90.9
 PL-120.90.91.00.9
 PL-141.31.11.00.8
  • NOTE. The surviving clones obtained from single step paclitaxel selection were tested for drug sensitivity by MTT assay. Values are average of three experiments.