Table 1

Therapy for SKOV3ip1 tumors implanted orthotopically in nude mice

Treatment groupIncidenceaMean tumor weight ± SD (g)Mean ascites (ml)Mean body weight (g)
Control10/101.0 ± 0.61.522.0
Paclitaxel10/100.4b ± 0.20.025.4b
STI57110/100.9 ± 0.51.422.1
Paclitaxel + STI5717/100.1c ± 0.10.0d24.7d
  • a Number of mice with tumor/number of mice injected.

  • b P < 0.05 compared with control and STI571 alone.

  • c P < 0.05 compared with all other groups, including paclitaxel alone.

  • d P < 0.01 compared with control and STI571 alone.