Table 2

Therapy for Hey A8 tumors implanted orthotopically into nude mice

Treatment groupIncidenceaMean tumor weight ± SD (g)Mean body weight ± SD (g)
Control10/102.2 ± 0.924.4 ± 1.2
Paclitaxel9/101.1b ± 0.723.8 ± 1.7
STI57110/101.9 ± 0.824.1 ± 1.0
Paclitaxel + STI5717/100.5c ± 0.424.5 ± 0.9
  • a Number of mice with tumor/number of mice injected.

  • b P < 0.01 compared with control and STI571 alone.

  • c P < 0.05 compared with all other groups, including paclitaxel alone.