Table 3

Bacteriocidal activity of sera from patients vaccinated with NP-polySA-KLHa plus QS-21 against group B meningococcus

PatientWeekBacteriocidal activity: antisera dilution able to give
80% Killing50% Killing
11200500
4>10000>10000
103000>10000
21No200
4>10000>10000
31No200
4100200
41No200
425007000
51No200
415004500
61No200
42000>10000
  • a PolySA, polysialic acid; NP, N-propionylated; KLH, keyhole limpet hemocyanin.