Table 7

Drug-related adverse events with an incidence of ≥5%

Drug-related adverse eventa250 mg/day (n = 102) (%)500 mg/day (n = 114) (%)
Diarrhea49 (48)76 (67)
Rash44 (43)61 (54)
Acne25 (25)37 (33)
Dry skin13 (13)30 (26)
Nausea13 (13)20 (18)
Vomiting12 (12)10 (9)
Pruritus8 (8)10 (9)
Anorexia7 (7)11 (10)
Asthenia6 (6)5 (4)
Weight loss3 (3)6 (5)
  • a A patient may have had more than one drug-related adverse event.