Table 1

Patient characteristics and correlation with cytokeratin-positive (CK+) cell detection in bone marrow and peripheral blood in 75 nonmetastatic patients

n (%)CK+ cells in bone marrow (%)PCK+ cells in peripheral blood (%)P
Menopausal status
 Pre43 (57)26 (60.5)8 (19)
 Post32 (43)11 (34)0.0244 (12.5)0.471
Clinical tumor size
 T1/T239 (52)13 (33)3 (7.5)
 T320 (27)12 (60)5 (25)
 T416 (21)12 (75)0.0254 (25)0.35
Clinical nodal status
 N036 (48)16 (44.5)6 (17)
 N132 (43)16 (50)4 (15)
 N27 (9)5 (71.5)0.3312 (28.5)0.879
Hormone receptors
 Estrogen receptor+44 (59)17 (38.6)4 (9)
 Estrogen receptor−31 (41)20 (64.5)0.0268 (26)0.053
 Progesterone receptor+14 (19)6 (43)1 (7)
 Progesterone receptor−45 (60)26 (58)0.32811 (24.5)0.126
 Missing16 (21)
Tumor grade
 I12 (16)5 (42)0 (0)
 II27 (36)10 (37)3 (11)
 III34 (45)22 (65)0.0799 (26.5)0.066
 Missing2 (3)
Tumor emboli
 Negative40 (53)16 (40)4 (10)
 Positive33 (44)21 (64)0.0438 (24)0.101
 Missing2 (3)
Histological nodal status
 pN023 (31)15 (65)7 (30)
 pN148 (64)21 (44)0.0885 (10)0.041
 Missing4 (5)
 pN <3N+38 (51)19 (50)9 (24)
 pN >3N+33 (44)17 (52)0.8983 (9)0.094
 Missing4 (5)
Histology
 Ductal65 (87)33 (51)11 (17)
 Lobular9 (12)4 (44)1 (11)
 Other1 (1)0 (0)0.5730 (0)0.822