Table 2

IC50s for known NAD(P)H:quinone oxidoreductase (NQO1) substrates

CompoundIC50 (nm)
MDA468NQ16
Streptonigrin212.2 ± 17.42.2 ± 1.4a
Menadione5600 ± 11009200 ± 1300a
RH130 ± 2.73.2 ± 1.7a
  • a A significant difference (P < 0.05) between IC50s for MDA468 and NQ16 cells.