Table 2.

Distribution of relapsed and disease-free patients according to TS combined genotypes

GroupCombined genotypes (5′-UTR + 3′-UTR)Total (N = 90)Disease free (n = 36)Relapsed (n = 54)P*
ALow + Low25 (28%)16 (64%)9 (36%)0.003
BLow + High19 (21%)8 (42%)11 (58%)
CHigh + Low36 (40%)12 (33%)24 (67%)
DHigh + High10 (11%)0 (0%)10 (100%)
  • * P value of the χ2 test.

  • Carriers of TS5′-UTR 2R/2R, 2R/3C, 3C/3C, TS3′-UTR ins6/del6, and del6/del6 genotypes are classified as low TS producers.

  • Carriers of TS3′-UTR ins6/ins6 and TS5′-UTR 3G/3G, 3G/3C, 3G/2C genotypes are classified as high TS producers.