Table 2.

Maximum selected nonhematologic and hematologic toxicities by grade (n = 28)

No. patients experiencing toxicity all courses (%)
ToxicityGrade IGrade IIGrade IIIGrade IV
Alopecia15 (53.6)8 (28.6)
Anorexia12 (42.9)6 (21.4)1 (3.6)
Aspartate serum transferase increase1 (3.6)2 (7.1)
Creatinine increase6 (21.4)2 (7.1)1 (3.6)
Deep vein thrombosis1 (3.6)1 (3.6)1 (3.6)
Diarrhea14 (50)2 (7.1)5 (17.9)
Fatigue6 (21.4)10 (35.7)5 (17.9)
Febrile neutropenia1 (3.6)5 (17.9)1 (3.6)
Headache9 (32.1)
Hypophosphatemia2 (7.1)6 (21.4)
Hyperlacrimation3 (10.7)
Myalgia12 (42.9)
Limb edema4 (14.3)1 (3.6)
Pyrexia17 (60.7)4 (14.7)
Sensory neuropathy2 (7.1)
Stomatitis3 (10.7)1 (3.6)
Vomiting10 (35.7)
Nausea9 (32.1)7 (25)1 (3.6)
Anemia3 (10.7)2 (7.1)1(3.6)
Neutropenia7 (25)19 (67.9)
Thrombocytopenia1 (3.6)