Maximum selected nonhematologic and hematologic toxicities by grade (n = 28)
| No. patients experiencing toxicity all courses (%) | |||||||
|---|---|---|---|---|---|---|---|
| Toxicity | Grade I | Grade II | Grade III | Grade IV | |||
| Alopecia | 15 (53.6) | 8 (28.6) | |||||
| Anorexia | 12 (42.9) | 6 (21.4) | 1 (3.6) | ||||
| Aspartate serum transferase increase | 1 (3.6) | 2 (7.1) | |||||
| Creatinine increase | 6 (21.4) | 2 (7.1) | 1 (3.6) | ||||
| Deep vein thrombosis | 1 (3.6) | 1 (3.6) | 1 (3.6) | ||||
| Diarrhea | 14 (50) | 2 (7.1) | 5 (17.9) | ||||
| Fatigue | 6 (21.4) | 10 (35.7) | 5 (17.9) | ||||
| Febrile neutropenia | 1 (3.6) | 5 (17.9) | 1 (3.6) | ||||
| Headache | 9 (32.1) | ||||||
| Hypophosphatemia | 2 (7.1) | 6 (21.4) | |||||
| Hyperlacrimation | 3 (10.7) | ||||||
| Myalgia | 12 (42.9) | ||||||
| Limb edema | 4 (14.3) | 1 (3.6) | |||||
| Pyrexia | 17 (60.7) | 4 (14.7) | |||||
| Sensory neuropathy | 2 (7.1) | ||||||
| Stomatitis | 3 (10.7) | 1 (3.6) | |||||
| Vomiting | 10 (35.7) | ||||||
| Nausea | 9 (32.1) | 7 (25) | 1 (3.6) | ||||
| Anemia | 3 (10.7) | 2 (7.1) | 1(3.6) | ||||
| Neutropenia | 7 (25) | 19 (67.9) | |||||
| Thrombocytopenia | 1 (3.6) | ||||||