Table 1.

Assumptions used in the clinical trials of BPA-based BNCT for calculation of the 10B(n,α)7Li component of the Gy(w) dose in various tissues

TissueBoron concentration*CBE factor
BloodMeasured directly
Brain1.0 times blood (27, 28)1.3 (23)
Scalp/skin1.5 times blood (2628)2.5 (26)
Tumor3.5 times blood (162)3.8 (21)
  • * A RBE of 3.2 is used for the high LET component of the beam dose: protons from the 14N(n,n)14C reaction and the recoil protons from fast neutron collisions with hydrogen. Literature references are given in parentheses.