Table 1.

Patient characteristics of men with no evidence of cancer on prostate biopsy and men with clinically localized prostate cancer treated with radical prostatectomy

Biopsy negative, n = 46 (%)Clinically localized cancer, initial cohort, n = 85 (%)
Age (y)
    Mean60.258.6
    Range40-7940-71
PSA (ng/mL)
    Mean2.36.2
    Range0.1-4.00.9-15.5
Pathologic Gleason score*
    5-665 (76)
    717 (20)
    8-102 (2)
Pathologic stage
    Organ confined78 (92)
    Nonorgan confined7 (8)
    Positive extraprostatic extension6 (7)
    Positive seminal vesicle invasion1 (1)
    Positive surgical margins2 (2)
No. with GSTP1 CpG island hypermethylation detected010 (12)
GSTP1 CpG island hypermethylation index (range)00-30.3
  • * Pathologic Gleason score unavailable for one patient with clinically localized disease.