Table 2.

Immune responsiveness of patients

Immune response to vaccinationPatient no.No. prior regimensNo. vaccinationsImmune response
PHACEFCyp1B1
+11121,24448143
+20121,03877927
+52121,679149157
+11271,69955577
+14281,43813179
+1531254855920
Medians2.012.0
31546415513
43980715035
6211989192239
7612528328313
8531,759139201
9361,12237630
104274266012
1241239350
13369191,01862
1656338167269
174631410020
Medians4.06.0
Healthy donors
Z251,99813529
Z261,03011113
Z271,15630332
Z346625812
Z381,286Not done27
Z441,2962156
Z39Out of range53
Mean1,23813817
  • NOTE: Immune response measured as spots on IFN-γ ELISPOT in response to PHA, CEF, and CYP1B1.

    Abbreviations: PHA, phyto-hemagglutinin; CEF, pooled peptides from cytomegalovirus, Epstein Barr virus, and influenza virus; CYP1B1, nonoverlapping peptides from full-length CYP1B1, measured as baseline response.