Table 5.

Amounts of total catechin (mg) recovered in the urine over 24 hours after oral administration of Polyphenon E in the absence or presence of food

CatechinPolyphenon E (400 mg epigallocatechin gallate)
Polyphenon E (800 mg epigallocatechin gallate)
Polyphenon E (1,200 mg epigallocatechin gallate)
FedFastingFedFastingFedFasting
Epigallocatechin4.85 ± 1.83*2.67 ± 1.255.54 ± 1.594.49 ± 3.156.48 ± 4.105.39 ± 3.09
Epicatechin4.62 ± 1.762.64 ± 1.136.49 ± 2.285.26 ± 3.549.20 ± 6.256.44 ± 4.11
  • * Mean ± 1 SD.

  • Significantly different from the fed condition, P < 0.005 when data were pooled from all doses.

  • Significantly different from the fed condition, P < 0.0005 when data were pooled from all doses.