Table 1

AP-2α expression within gliomas among WHO grades

Histology (WHO grade)nAP-2α expression, n (%)95% CI*P
Low-grade astrocytoma (2)99 (100)66-100___
Oligodendroglioma (2)3729 (78)62-900.32
Mixed oligoastrocytoma (3)1512 (80)52-960.27
Anaplastic astrocytoma (3)491 (2)0-11<0.001
Anaplastic oligodendroglioma (3)3713 (35)20-53<0.001
Anaplastic mixed oligoastrocytoma (3)2012 (60)36-810.03
Glioblastoma (4)721 (1)0-7<0.001
Gliosarcoma (4)72 (29)4-710.005
  • NOTE: A tissue array was established that contained specimens of resected tumors (encompassing all WHO grades) from patients with gliomas. The expression of AP-2α was determined by immunohistochemistry.

  • * For the proportion with AP-2α expression.

  • As determined by Fisher's exact test in comparison with low-grade astrocytoma.