Table 3.

Patient characteristics

No.FASAYAgeStageGradeRecurrenceFollow-up (mo)p53 immunohistochemistry (%)p21 immunohistochemistry (%)Real-time PCR
TP53*p21*
1Nonfunctional81Ta3Yes29≥50<101,147 ± 152960 ± 151
2Nonfunctional77Ta3Yes710-50 (strong intensity)≥10NDND
3Nonfunctional62T13Yes3≥50<10471 ± 9353 ± 2
4Nonfunctional56T13Yes6≥50<10173 ± 877 ± 4
5Nonfunctional67T23CystectomyNDND78 ± 737 ± 2
6Nonfunctional76Ta3No28≥50<1012 ± 327 ± 1
7Nonfunctional73Ta3Yes7≥50≥10356 ± 772,100 ± 255
8Nonfunctional88Ta3Yes16≥50≥10NDND
9Nonfunctional82T23CystectomyNDNDNDND
10Nonfunctional77Ta3Yes13≥50NDNDND
11Nonfunctional67Ta3No11<10NDNDND
12Nonfunctional66T33Cystectomy≥50<10NDND
13Nonfunctional81T13No11≥50NDNDND
14Nonfunctional69T12No6≥50NDNDND
15Nonfunctional72T13No6>50NDNDND
16Nonfunctional/partially functional63T43Cystectomy<10≥10NDND
17Partially functional73Ta2No1910-50 (strong intensity)NDNDND
18Partially functional68T13No1810-50 (strong intensity)NDNDND
19Partially functional76T23Cystectomy≥50<10NDND
20Functional58Ta1No33<10NDNDND
21Functional75Ta3Yes5<10NDNDND
22Functional81Ta2No33<10≥1023 ± 2250 ± 13
23Functional67Ta1No3310-50 (weak intensity)NDNDND
24Functional77T13Yes510-50 (strong intensity)≥10120 ± 16240 ± 34
25Functional68Ta1No32<10≥10NDND
26Functional78Ta2Yes1110-50 (weak intensity)≥1015,979 ± 7834,900 ± 359
27Functional68Ta1No3210-50 (weak intensity)≥104,064 ± 4591,060 ± 192
28Functional86Ta2Yes15<10≥1025 ± 833 ± 3
29Functional81Ta1No32<10≥10NDND
30Functional67Ta1No3110-50 (weak intensity)≥101,645 ± 1564,570 ± 441
31Functional73Ta1No3110-50 (strong intensity)≥102,075 ± 81445 ± 17
32Functional75T13No3110-50 (weak intensity)<10340 ± 153,000 ± 221
33Functional73Ta3No30<10≥10270 ± 29260 ± 11
34Functional74Ta3No29<10≥10335 ± 381,760 ± 146
35Functional79Ta2No29<10≥10140 ± 221,030 ± 118
36Functional55Ta2No29<10≥10611 ± 71440 ± 53
37Functional76Ta3No2810-50 (weak intensity)≥1099 ± 1083 ± 11
38Functional64Ta1No28≥50≥10116 ± 179 ± 1
39Functional71Ta1No28NDND50 ± 2170 ± 16
40Functional78Ta1No2810-50 (weak intensity)≥1025,689 ± 2,6411,500 ± 195
41Functional77Ta2Yes19<10≥10NDND
42Functional78T23Cystectomy<10≥106,334 ± 2793,000 ± 191
43Functional70Ta2No1110-50 (weak intensity)≥10NDND
44Functional75Ta1No11<10≥10NDND
45Functional76Ta2No11NDNDNDND
46Functional43Ta1No610-50 (strong intensity)≥10NDND
47Functional89Ta1No6<10≥10NDND
48Functional81Ta1No6<10≥10NDND
49Functional52Ta2No6<10≥10NDND
50Functional77Ta3No6<10≥10NDND
51Functional82T13No6≥50≥10NDND
52Functional79Ta3No610-50 (strong intensity)≥10NDND
  • Abbreviation: ND, not determined.

  • * Percent of gene expression in tumoral tissue compared with normal tissue. Each value is the mean ± SD calculated on three independent experiments.