Table 1.

Baseline patient characteristics

Characteristicsn (%)
Gender
    Male39 (59)
No. prior chemotherapy regimens
    117 (26)
    222 (33)
    320 (30)
    4-87 (11)
Stage (Durie salmon)
    I5 (8)
    II46 (69)
    III15 (23)
Plasma cells in bone marrow aspirate (%)
    ≤5051 (77)
    >5013 (20)
    Dry specimen1 (2)
    Not done1 (2)
Disease state on commencing thalidomide
    Relapsed52 (79)
    Refractory or transient response to prior treatment14 (21)
ECOG performance status
    024 (36)
    124 (36)
    214 (21)
    Unknown4 (7)
Hemoglobin, <100 g/L23 (35)
Platelets, 50-150 × 109/L18 (28)
Neutrophils, <1.0 × 109/L11 (17)
β2-Microglobulin (mg/L)
    ≤326 (39)
    >3 to <623 (35)
    ≥616 (24)
    Not done1 (2)
LDH
    <UNL54 (82)
    >UNL10 (15)
    Not done2 (3)
CA153
    ≤UNL41 (62)
    >UNL to 2× UNL11 (17)
    ≥2× UNL3 (5)
    Not done11 (17)
  • Abbreviations: ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase.