Table 2.

Summary of thalidomide treatment received

Thalidomide/celecoxibThalidomide*P
n6658
Duration on treatment (wk)
    Median (95% CI)27 (18-41)24 (16-42)0.8
Total thalidomide dose (g)
    Median (95% CI)64 (39-105)66 (50-180)0.18
Average daily thalidomide dose (mg)
    Median (range)329 (85-727)398 (82-767)0.018§
Maximum daily thalidomide dose (mg/d)
    Median4006000.01§
    Range200-800200-1,000
        20011 (17%)8 (14%)
        3003 (5%)1 (2%)
        40027 (41%)16 (28%)
        5001 (2%)1 (2%)
        60012 (18%)5 (9%)
        80012 (18%)25 (43%)
        9000 (0%)1 (2%)
        1,0000 (0%)1 (2%)
  • * Prior thalidomide trial (44).

  • Up to close-out date.

  • Log-rank test.

  • § Wilcoxon rank sum test.