Table 3.

Haplotype linked to the mutated allele at the CDH1 locus in the three HDGC families harboring the c.1003C>T germ line mutation

MicrosatelliteSwedish family (4/5)*F1 (6/8)*F3 (1/3)*
D16S503 (17213228)†228233220
D16S3025 (22180595)9287101
CDH1 (22385518)+++
D16S496 (22562909)220217217
D16S3095 (23560429)150150152
D16S752 (24949389)102114110
D16S512 (27681791)257262260

  • ↵* Number of affected members versus number of members analyzed.

  • ↵† Microsatellite marker position.