Patient disposition at the time of data cutoff
| Letrozole, n = 2,583 | Placebo, n = 2,587 | Total, n = 5,170 | ||||
|---|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | ||||
| No. patients treated | 2,567 (99.4) | 2,569 (99.3) | 5,136 (99.3) | |||
| Treatment completed | 6 (0.2) | 8 (0.3) | 14 (0.3) | |||
| Ongoing at time of data cutoff | 1,934 (74.9) | 1,884 (72.8) | 3,818 (73.8) | |||
| Discontinued | 627 (24.3) | 677 (26.2) | 1,304 (25.2) | |||
| Reasons for treatment discontinuation | ||||||
| Patient refusal | 303 (11.7) | 293 (11.3) | 596 (11.5) | |||
| Toxicity of therapy | 127 (4.9) | 95 (3.7) | 222 (4.3) | |||
| Other | 101 (3.9) | 136 (5.3) | 237 (4.6) | |||
| Recurrent disease | 58 (2.2) | 109 (4.2) | 167 (3.2) | |||
| Intercurrent illness | 22 (0.9) | 24 (0.9) | 46 (0.9) | |||
| Death | 16 (0.6) | 18 (0.7) | 34 (0.7) | |||
| Protocol violation | 0 (0.0) | 1 (0.0) | 1 (0.0) | |||
| Unknown | 0 (0.0) | 1 (0.0) | 1 (0.0) | |||