Table 1.

Participant characteristics

VariableHNSCC cases (n = 58)Healthy controls (n = 29)P
Age, y
    Median (range)63.0 (30-86)69.0 (25-82)0.20
    Mean ± SD64.4 ± 11.165.7 ± 14.4
Gender (%)
    Male41 (70.7)21 (72.4)0.87
    Female17 (29.3)8 (27.6)
Alcohol use (%)
    Never9 (15.5)7 (24.1)0.45
    Former18 (31.0)2 (6.9)
    Current31 (53.5)20 (69.0)
Tobacco use (%)
    Never18 (31.0)16 (55.2)0.03
    Former27 (46.6)11 (37.9)
    Current13 (22.4)2 (6.9)
Pack-year exposure*
    Median (range)28.5 (0.2-97.5)20.0 (8.0-144.0)0.96
    Mean ± SD32.4 ± 24.839.9 ± 40.5
Daily aspirin use
    81 mg (%)10 (17.2)10 (34.5)0.07
  • * Pack-year exposure refers to 49 ever smokers (36 HNSCC cases and 13 healthy controls) and excludes four exclusive pipe smokers.