Table 2

Association of HLA class I antigen down regulation in primary ovarian carcinoma lesions with disease stage

HLA class I antigens
TAP
++
Grade
    G16 (66.6%)3 (33.3%)7 (77.7%)2 (22.2%)
    G213 (72.2%)5 (27.7%)16 (88.9%)2 (11.1%)
    G313 (54.2%)11 (45.8%)18 (75.0%)6 (25.0%)
K-WNSNS
Log-LinNSNS
Stage
    I4 (80.0%)1 (20,0%)4 (80.0%)1 (20.0%)
    II20 (80.0%)5 (20.0%)23 (92.0%)2 (8.0%)
    III7 (35.0%)13 (65.0%)*13 (65.0%)7 (35.0%)
    IV1
*K-WP < 0.005NS
Log-LinNSNS
  • NOTE: All percentages were calculated on the total number of patients with each phenotype. The case classified as stage IV was excluded from the statistical analysis. K-W: The Kruskal-Wallis test was used to determine the association between ordinal and nominal variables (grade and stage were considered as ordinal variables). Log-Linear models. For each variable, a test of partial association is shown.

  • * The interactions between TAP and HLA class I antigen phenotypes were not significantly associated at the 0.05 level.